Die Deutsche Gesellschaft für Angewandte Endokrinologie (DGAE) wurde am 01.09.1991 gegründet. Gründungsmitglieder waren vor allem niedergelassene Endokrinologen, die eine wissenschaftliche Basis für die Probleme der Endokrinologie in der täglichen Praxis schaffen wollten. Wissenschaftliche Tagungen mit schwerpunktmäßiger Thematik der praktisch-klinischen Endokrinologie finden seither in Form von Jahrestagungen und Kleinkonferenzen statt. Aspekte der Qualitätskontrolle, Weiterbildung, Ökonomie und Gesundheitspolitik sind die Voraussetzungen für die tägliche Umsetzung der Wissenschaftlichen Erkenntnisse in Klinik und Praxis. Hormonstörungen und ihre Beachtung, die Prophylaxe und die Rolle der Endokrinologie, insbesondere auch für die älter werdende Generation, bei ständig steigendem Lebensalter der Bevölkerung in der modernen Industriegesellschaft, gehören zu den Aufgaben der DGAE.
Die Deutsche Gesellschaft für Angewandte Endokrinologie versteht sich vor allem in der Wahrnehmung einer Vermittlerrolle zwischen Forschung, stationärer Diagnostik und Therapie von Hormonstörungen bei Menschen aller Altersgruppen. Der integrative Aspekt der Hormonstörung in allen Bereichen der Medizin verlangt eine intensive und aktuelle Information der endokrinologisch tätigen Ärzte.
Lesen Sie hier die Satzung der DGAE.
Vorstand

PD Dr. med. Gesine Meyer
Präsidentin
Oberärztin der endokrinologischen/diabetologischen Hochschulambulanz am MainMed. Klinik I
Universitätsklinikum Frankfurt

Prof. Dr. med. Jörg Bojunga
Vizepräsident
Leiter Schwerpunkt Endokrinologie, Diabetologie, ErnährungsmedizinStv. Direktor
Internistische Intensivmedizin - DEGUM III Kursleiter
Medizinische Klinik I
Universitätsklinikum Frankfurt

Dr. med. Sven-Martin Schlaffer
Schatzmeister
OberarztNeurochirurgische Klinik
Universitätsklinikum Erlangen
ab 01.09.2024
Kompetenzzentrum für Wirbelsäulen- & Hypophysenchirurgie
Nürnberg
 
 
 
Beirat der DGAE
 

 
Fachärztin für Innere Medizin
Fachärztin für Endokrinologie/Diabetologie
Medicover Berlin

 
Ärztin für Innere Medizin, Schwerpunkt Endokrinologie, Diabetologin DDG
Deutsche Klinik für Diagnostik
Wiesbaden
 
23.05. - 24.05.2025 Jahrestagung der DGAE in Bayreuth
Schilddrüsensonographiekurse nach DEGUM-Richtlinien, Frankfurt
- Modul II am 12.11.2025 09:00 Uhr bis 14.11.2025 um 17:00 Uhr
Kurse werden als Präsenz- und Onlineveranstaltung stattfinden. Der Veranstaltungsort wird die Sonographieeinheit des Universitätsklinikums Frankfurt, Haus 23 EG sein.
Anmeldung: über die Landesärztekammer Hessen ( http://www.akademie-laekh.de) Frau Juliane Schwab, Email: juliane.schwab@laekh.de Tel. 06032 782-211
24.10.-25.10.2025 – „Geriatrie meets Endokrinologie“ in Berlin
Anmeldungen können über folgende Emailadresse erfolgen: Andrea.Willenberg@unimedizin-ffm.de
Das Programm mit allen weiteren Informationen finden Sie hier:
d) Workshop Hypophyse im Herbst 2026 in Frankfurt
Literaturupdates Endokrinologie
Jörg Bojunga, Frankfurt
Liebe Kolleginnen und Kollegen, liebe DGAE-Mitglieder!
Auf diese Seite finden Sie aktuelle Literatur zu Themen der Endokrinologie und angrenzender Gebiete. Die Veröffentlichungen sind thematisch sortiert, Sie können die Literatur direkt über den Link einsehen. Der download der vollständigen Veröffentlichung ist zum Teil frei möglich. Wir haben auf eine Kommentierung verzichtet, dafür aber eine größere Anzahl an Literatur zur Verfügung gestellt, die keinen Anspruch auf Vollständigkeit erhebt. Für Kommentare und Fragen sind wir dankbar, gerne jederzeit unter dgae.info@t-online.de.
Klicken Sie auf die folgenden Themen, um Vorträge und Fachartikel der DGAE zu lesen und herunterzuladen:Endokrine Onkologie (Nebenniere, Schilddrüse)
2. Fassnacht M, Assie G, Baudin E, Eisenhofer G, de la Fouchardiere C, Haak HR, et al. Adrenocortical carcinomas and malignant phaeochromocytomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2020;31(11):1476-90.
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5. Giordano TJ. The Argument for Mitotic Rate-based Grading for the Prognostication of Adrenocortical Carcinoma. The American Journal of Surgical Pathology. 2011;35(4):471-3.
6. Giordano TJ, Berney D, de Krijger RR, Erickson L, Fassnacht M, Mete O, et al. Data set for reporting of carcinoma of the adrenal cortex: explanations and recommendations of the guidelines from the International Collaboration on Cancer Reporting. Hum Pathol. 2021;110:50-61.
7. Hendricks A, Müller S, Fassnacht M, Germer CT, Wiegering VA, Wiegering A, et al. Impact of Lymphadenectomy on the Oncologic Outcome of Patients with Adrenocortical Carcinoma- A Systematic Review and Meta-Analysis. Cancers (Basel). 2022; 7;14(2):291. https://doi.org/10.3390/cancers14020291.
8. Kimpel O, Bedrose S, Megerle F, Berruti A, Terzolo M, Kroiss M, et al. Adjuvant platinum-based chemotherapy in radically resected adrenocortical carcinoma: a cohort study. Br J Cancer. 2021;125(9):1233-8.
9. Roux C, Boileve A, Faron M, Lamartina L, Delpla A, Tselikas L, et al. Loco-Regional Therapies in Oligometastatic Adrenocortical Carcinoma. Cancers (Basel). 2022;14(11) , 2730; https://doi.org/10.3390/cancers14112730.
10. Landwehr LS, Altieri B, Schreiner J, Sbiera I, Weigand I, Kroiss M, et al. Interplay between glucocorticoids and tumor-infiltrating lymphocytes on the prognosis of adrenocortical carcinoma. J Immunother Cancer. 2020;8(1) :e000469. https://doi.org/10.1136/jitc-2019-000469.
11. Baechle JJ, Hanna DN, Sekhar KR, Rathmell JC, Rathmell WK, Baregamian N. Integrative computational immunogenomic profiling of cortisol-secreting adrenocortical carcinoma. J Cell Mol Med. 2021;25(21):10061-72.
12. Mete O, Asa SL, Gill AJ, Kimura N, de Krijger RR, Tischler A. Overview of the 2022 WHO Classification of Paragangliomas and Pheochromocytomas. Endocr Pathol. 2022;33(1):90- 114.
13. Nölting S, Bechmann N, Taieb D, Beuschlein F, Fassnacht M, Kroiss M, et al. Personalized Management of Pheochromocytoma and Paraganglioma. Endocrine Reviews. 2021;43(2):199-239.
14. Hadoux J, Favier J, Scoazec J-Y, Leboulleux S, Al Ghuzlan A, Caramella C, et al. SDHB mutations are associated with response to temozolomide in patients with metastatic pheochromocytoma or paraganglioma. International Journal of Cancer. 2014;135(11):2711- 20.
15. Perez K, Jacene H, Hornick JL, Ma C, Vaz N, Brais LK, et al. SDHx mutations and temozolomide in malignant pheochromocytoma and paraganglioma. Endocr Relat Cancer. 2022 19;29(9):533-544. https://doi.org/10.1530/ERC-21-0392.
16. Calissendorff J, Juhlin CC, Sundin A, Bancos I, Falhammar H. Adrenal myelolipomas. Lancet Diabetes Endocrinol. 2021;9(11):767-75.
17. Incampo G, Di Filippo L, Grossrubatscher EM, Dalino Ciaramella P, Frara S, Giustina A, et al. Adrenal schwannoma: why should endocrinologists be aware of this uncommon tumour? Endocrine. 2022;75(3):684-97.
18. Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, et al. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2016;26(1):1- 133.
19. Leboulleux S, Bournaud C, Chougnet CN, Zerdoud S, Al Ghuzlan A, Catargi B, et al. Thyroidectomy without Radioiodine in Patients with Low-Risk Thyroid Cancer. N Engl J Med. 2022;386(10):923-32.
20. Durante C, Puxeddu E, Ferretti E, Morisi R, Moretti S, Bruno R, et al. BRAF Mutation s in papillary thyroid carcinomas inhibit genes involved in iodine metabolism. J Clin Endocrinol Metab. 2007;92(7):2840-3.
21. Ho AL, Dedecjus M, Wirth LJ, Tuttle RM, Inabnet WB, 3rd, Tennvall J, et al. Selumetinib Plus Adjuvant Radioactive Iodine in Patients With High-Risk Differentiated Thyroid Cancer: A Phase III, Randomized, Placebo-Controlled Trial (ASTRA). J Clin Oncol. 2022;40(17):1870- 8.
22. Schlumberger M, Tahara M, Wirth LJ, Robinson B, Brose MS, Elisei R, et al. Lenvatinib versus placebo in radioiodine-refractory thyroid cancer. N Engl J Med. 2015;372(7):621-30.
23. Brose MS, Robinson B, Sherman SI, Krajewska J, Lin CC, Vaisman F, et al. Cabozantinib for radioiodine-refractory differentiated thyroid cancer (COSMIC-311): a randomised, double- blind, placebo-controlled, phase 3 trial. Lancet Oncol. 2021;22(8):1126-38.
24. Elisei R, Schlumberger MJ, Müller SP, Schöffski P, Brose MS, Shah MH, et al. Cabozantinib in progressive medullary thyroid cancer. J Clin Oncol. 2013;31(29):3639-46.
25. Koehler VF, Adam P, Frank-Raue K, Raue F, Berg E, Hoster E, et al. Real-World Efficacy and Safety of Cabozantinib and Vandetanib in Advanced Medullary Thyroid Cancer. Thyroid. 2021;31(3):459-69.
26. Koehler VF, Berg E, Adam P, Weber GL, Pfestroff A, Luster M, et al. Real-World Efficacy and Safety of Multi-Tyrosine Kinase Inhibitors in Radioiodine Refractory Thyroid Cancer. Thyroid. 2021;31(10):1531-41.
27. Wirth LJ, Sherman E, Robinson B, Solomon B, Kang H, Lorch J, et al. Efficacy of Selpercatinib in RET-Altered Thyroid Cancers. N Engl J Med. 2020;383(9):825-35.
28. Subbiah V, Hu MI, Wirth LJ, Schuler M, Mansfield AS, Curigliano G, et al. Pralsetinib for patients with advanced or metastatic RET-altered thyroid cancer (ARROW): a multi- cohort, open-label, registrational, phase 1/2 study. Lancet Diabetes Endocrinol. 2021;9(8):491-501.
29. Lee YA, Lee H, Im SW, Song YS, Oh DY, Kang HJ, et al. NTRK and RET fusion-directed therapy in pediatric thyroid cancer yields a tumor response and radioiodine uptake. J Clin Invest. 2021;131(18).
30. Groussin L, Bessiene L, Arrondeau J, Garinet S, Cochand-Priollet B, Lupo A, et al. Letter to the Editor: Selpercatinib-Enhanced Radioiodine Uptake in RET-Rearranged Thyroid Cancer. Thyroid. 2021;31(10):1603-4.
31. Dias-Santagata D, Lennerz JK, Sadow PM, Frazier RP, Govinda Raju S, Henry D, et al. Response to RET-Specific Therapy in RET Fusion-Positive Anaplastic Thyroid Carcinoma. Thyroid. 2020;30(9):1384-9.
32. Subbiah V, Kreitman RJ, Wainberg ZA, Cho JY, Schellens JHM, Soria JC, et al. Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study. Ann Oncol. 2022;33(4):406-15.
33. Subbiah V, Kreitman RJ, Wainberg ZA, Cho JY, Schellens JHM, Soria JC, et al. Dabrafenib and Trametinib Treatment in Patients With Locally Advanced or Metastatic BRAF V600- Mutant Anaplastic Thyroid Cancer. J Clin Oncol. 2018;36(1):7-13.
34. Wirth LJ, Brose MS, Sherman EJ, Licitra L, Schlumberger M, Sherman SI, et al. Open-Label, Single-Arm, Multicenter, Phase II Trial of Lenvatinib for the Treatment of Patients With Anaplastic Thyroid Cancer. J Clin Oncol. 2021;39(21):2359-66.
35. Dierks C, Seufert J, Aumann K, Ruf J, Klein C, Kiefer S, et al. Combination of Lenvatinib and Pembrolizumab Is an Effective Treatment Option for Anaplastic and Poorly Differentiated Thyroid Carcinoma. Thyroid. 2021;31(7):1076-85.
Andrologie
2. Aprea I, Raidt J, Höben IM, Loges NT, Nöthe-Menchen T, Pennekamp P, Olbricht H, Kaiser T, Biebach L, Tüttelmann F, Horvath J, Schubert M, Krallmann C, Kliesch S, Omran H. Defects in the cytoplasmic assembly of axonemal dynein arms cause mrophological abnormalities and dysmotility in sperm cells leading to male infertility. PLOS Genetics 2021; https://doi.org/10.1371/journal.pgen.1009306.
3. Barnouin Y, Armamento-Villareal R, Celli A, Jiang B, Paudyal A, Nambi V, Bryant MS, Marcelli M, Garcia JM, Qualls C, Villareal DT. Testosterone replacement therapy added to intensive lifestyle intervention in older men with obesity and hypogonadism. JCEM 2021; 106: e1096-e1110
4. Chu KY, Nacjeeran S, Horodyski L, Masterson TA, Ramasamy R. COVID-19 infectin is associated with new onset erectile dysfunction: insights from a nation registry. Sex Med 2022; 10:100478
5. Dubin JM, White J, Ory J, Ramasamy R. Vasectomy reversal vs. sperm retrieval with in vitro fertilitzation: a contemporary, comparative analysis. Fertil Steril 2021; 115: 1377- 1383
6. Houston BJ, Riera Escamilla R, Wyrwoll MJ, et al. A systematic review oft he validated monogenic causes of human male infertility: 2020 update and a discussion of emerging genedisease relationships. Hum Reprod Update 2021; 28: 15-29
7. Jayasena CN, Anderson RA, Llahana S, Barth JH, MacKenzie F, wilkes S, Smith N, Sooriakumaran P, Minhas S, Wu FCW, Tomlinson J, Quinton R. Society for Endocrinology guidelines for testosterone replacement therapy in male hypogonadism. Clin Endocrinol 2021; 96: 200-219
8. Kliesch S. “Praktisches Spermiogramm” – Ejakulatdiagnostik gemäß WHO. Urologe 2021; 60:647-656
9. Kliesch S, Schmidt S, Wilborn D, Aigner C, Albrecht W, Bedke J et al. Albers P. Management of germ cell tumors of the testis in adult patients. German Clinical Practice Guideline Part I: Epidemiology, classification, diagnosis, prognosis, fertility preservation, and treatment recommendations for localized stages. Urol Int 2021; 05: 69-180
10. Krenz H, Sansone A, Kliesch S, Gromoll J, Schubert M. FSHB genotype identified as a relevant diagnostic parameter revealed by cluster analysis of men with idiopathic infertility. Frontiers in Endocrinology, 2021, 12: https://doi.org/10.3389/fendo.2021.780403.
11. Krenz H, Sansone A, Fujarski M, Krallmann C, Zitzmann M, Dugas M, Kliesch S, Varghese J, Tüttelmann F, Gromoll J. Machine learning based prediction models in male reproductive health: Development of a proof-of-concept model for Klinefelter Syndrome in azoospermic patients. Andrology 2022; 10: 534-544
12. Kulkarni V, Kaingade P, Kulkarni N, Bhalerao T, Nikam A. Assessment of semen parameters in consecutive ejalculates with short abstinence period in oligospermic males. J Assisted Reprod 2022; 26:310-314.
13. Lotti F, Firzza F, Balerica G, Barbonetti A, Behre HM, Calogero AE, Cremers JF, Francavilla F, Isidori AM, Kliesch S, La Vignera S, Lenzi A, Marcou M, Pilatz A, Poolamets O, Punab M, Godoy MFP, Rajmil O, Salvio G, Schaeer O, Weidner W, Maseroli E, Cipriani S, Baldi E, Degl ́Ínnocenti S, Danza G, Caldini AL, Trreni A, Boni L, Krausz C, Maggi M. The European Academy of Andrology (EAA) ultrasound study on healthy , fertile men: scrotal ultrasound reference ranges and associations with clinical, seminal and biochemical chracteristics. Andrology 2021, 9:559-576
14. Lotti F, Firzza F, Balerica G, Barbonetti A, Behre HM, Calogero AE, Cremers JF, Francavilla F, Isidori AM, Kliesch S, La Vignera S, Lenzi A, Marcou M, Pilatz A, Poolamets O, Punab M, Godoy MFP, Quintian C, Rajmil O, Salvio G, Schaeer O, Weidner W, Maseroli E, Cipriani S, Baldi E, Degl ́Ínnocenti S, Danza G, Caldini AL, Terreni A, Boni L, Krausz C, Maggi M. The European Academy of Andrology (EAA) ultrasound study on healthy, fertile men: Prostate-vesicular transrectal ultrasound reference ranges and associations with clinical, seminal and biochemical characteristics. Andrology 2022, June 23 https://doi.org/10.1111/andr.13217 online ahead of print.
15. Maijoub A, Tadros NN, Polackwich AS, Aharma R, Agarwal A, Sabanehg E. Vasectomy reversal semen analysis: new reference ranges predict pregnancy. Fertil Steril 2017;107:911- 915
16. Meitei HY, Uppangala S, Lashmi RV, Guddattu V, Jegde P, Kumar P, Adiga P, Kalthur G, Schlatt S, Adiga SK. Sperm characteristics in normal and abnomal ejaculates are differently influenced by the length of ejaculatory abstinence. Andrology 2022; https://doi.org/10.1111/andr.13222.
17. Myers J, Prakash M, Froelicher V, Do D, Partington S, Atwood JE. Exercise capacity and mortality among men referred for exercise testing. N Engl J Med 2002;346:793-801
18. Oud MS, Volozonoka L, Smits RM, Vissers L, Ramos L, Veltman JA. A systematic review and standardized clinical validity assessment of male infertility genes. Hum Reprod 2019; 34: 932- 941
19. Oud MS, Volozonoka L, Friedrich C, Kliesch S, Nagimaja L, Gillssen C, O ́Bryan MK, MacLachlan RI, Aston KI, Tüttelmann F et al. Lack of evidence for a role of PIWIL1 variants in human male infertility. Cell 202; 84: 1941-1942
20. Salas-Huetos A, Tüttelmann F, Wyrwoll MJ, Kliesch S, Lopes AM, Concalves J, Boyden SE, Wöste M, Hotaling JM, GEMINI Consortium, Nagirnaja L, Conrad DF, Carrell DT, Aston KI. Disruption of human meiotic telomere complex genes TERB1, TERB2 and MAJIN in men with non-obstructive azoospermia. Hum Genet 2021a; 140:218-227
21. Salas-Huetos A, Tüttelmann F, Wyrwoll MJ, Kliesch S, Lopes AM, Concalves J, Boyden SE, Wöste M, Hotaling JM, GEMINI Consortium, Nagirnaja L, Conrad DF, Carrell DT, Aston KI. Correction to: Disruption of human meiotic telomere complex genes TERB1, TERB2 and MAJIN in men with non-obstructive azoospermia. Hum Genet 2021b; 140:Erratum
22. Salonia A, Bettocchi C, Carvalho J, Corona G, Jones TH, Kadioglu A, Martinez-Salamanca JI, Minhas S, Serefoglu EC, Verze P. European Guidelines on Sexual and Reproductive Male Health. European Association of Urology 2020. https://uroweb.org/wp-content/uploads/EAU-Guidelines-on-Sexual-and-Reproductive-Health-2020.pdf
23. Schistermann EF, Sjaarda LA, Clemons T, Carrell T, Perkins NJ, Johnstone E, Lamb D, Chaney K, Van Voorhis BJ, Ryan G, Summers K, Hotaling J, Robins J, Mills J, Mendola P, Chen Z, DeVilbiss EA, Peterson cm, Mumford SL. Effect of Folic Acid and Zinc Supplementation in men on semen quality and live birth among couples undergoing infertility treatment. A randomized clinical trial. JAMA 2020;232:35-48.
24. Schubert M, Lanuza LP, Gromoll J. Pharmacogenetics of FSH action in the male. Front Endocrinol 2019; https://doi.org/10.3389/fendo.2019.00047. eCollection 2019
25. Schubert M, Pérez Lanuza L, Wöste M, Dugas M, Carmona FD, Palomino-Morales RJ, RassamY, Heilmann-Heimbach S, Tüttelmann F, Kliesch S, Gromoll J. A GWAS in idiopathic/unexplained infertile men detects a genomic region determing follicle- stimulating hormone levels. Journal Clinical Endocrinoloy & Metabolism, 2022, 107:2350-2361
26. Toure A, Martinez G, Kherraf ZE, Cazin C, Beurois J, Arnoult C, Ray PF, Coutton C. The genetic architecture of morphological abnormalities of the sperm tail. Hum Genet 2021; 140: 21-42
27. Tüttelmann F, Ruckert C, Röpke A. Disorders of spermatogenesis: Perspectives for novel genetic diagnostics after 20 years of unchanged routine. Med Genet. 2018;30(1):12-20. https://doi.org/10.1007/s11825-018-0181-7.
28. Uvin V, De Brucker S, De Brucker M, Vloeberghs V, Drakopoulos P, Santos-Ribeiro S, Tournaye H. Pregnancy after vasectomy: surgical reversal or assisted reproduction. Hum Reprod. 2018; 33:1218-1227
29. Verdi A, Nasr-Esfahani MH, Forouzanfar M, Tavalaee M. The effect of recombinant human follicle-stimulating hormone on sperm quality, chromatin structure and clinical outcomes of infertile oligozoospermic men candidate for intracytoplasmic sperm injection: A randomized clinical trial. Int J Fertil Steril 2021;15:1-7
30. Wensink MJ, Lu Y, Tian L, Shaw GM, Rizzi S, Kold Jensen T, Mathiesen ER, Skakkebaek NE, Lindahl-Jacobsen R, Eisenber ml. Preconception antidiabetic Drugs in men and birth defects in offspring. Ann Intern Med 2022, 175: https://doi.org/10.7326/M21-4389.
31. Wittert G, Bracken K, Robledo KP, Grossmann M, Yeap BB, Handelsman DJ, Stuckey B, Conway A, Inder W, McLachlan R, Allan C, Jesudason D, Fui MNT, Hague W, Jenkins A, Daniel M, Gebski V, Keech A. Testosterone treatment to prevent or revert type 2 diabetes in men enrolled in a lifestyle programme (T4DM): a randomized, double-blind, placebo-controlled, 2-year, phase 3b trial. Lancet Diabetes Endocrinol 2021; 9:32-45.
32. World Health Organization (WHO) Laboratory manual for examination and processing of human semen. 2021; 6. Aufl. WHO, Geneva. WHO laboratory manual for the examination and processing of human semen https://www.who.int/publications/i/item/9789240030787.
33. Wyrwoll MJ, Temel SG, Nagimaja L, OUd MS; Lopes AM, van der Heijden GW, Heald JS, Rotte N, Wistuba J, Wöste M, Ledig S, Krenz H, Smits RM, Carvalho F, Concalves J, Fietz D, Türkgenc, et al. Bi-allelic mutations in M1AP are a frequent cause of meiotic arrest and severely impaired spermatogenesis leading to male infertility. Am J Hum Genet 2020;107:342-351.
34. Wyrwoll MJ, Köckerling N, Vockel M, Dicke AK, Rotte N,Pohl E, Emich J, Wöste M, Ruckert C, Wabschke R, Seggewiss J, Ledig S, Tewes AC, Stratis Y, Cremers JF, Wistuba J, KRallmann C, Kliesch S, Röpke A, Stallmeyer B, Friedrich C, Tüttelmann F. Genetic Architecture of Azoospermia – Time to advance the standard of care. Eur Urol 2022, https://doi.org/10.1016/j.eururo.2022.05.011.
35. Yatsenko AN, Georgiadis AP, Röpke A, Berman AJ, Jaffe T, Olszewska M, Westernströer B, Sanfillippo J, Kurpisz M, Rajkovic A, Yatsenko SA, Kliesch S, Schlatt S, Tüttelmann F. X- linked TEX 11 mutations, meiotic arrest and azoospermia in infertile men. N Engl J Med 2015; 372:2097-2107
36. Zitzmann M, Aksglaede L, Corona G, Isidori AM, Juul A, T ́Sjoen G, Kliesch S, D ́Hauwers K, Toppari J, Slowikoska-Hilczer J, Tüttelmann F, Ferlin A. Academy of Andrology Guidelines on Klinefelter Syndrome. Andrology 2021; 9: 145- 167
37. Zitzmann M, Cremers JF, Krallmann C, Kliesch S. The HEAT-Registry (HEmatopoietic Affection by Testosteron): comparison of a transdermal gel vs long-acting intramuscular testosterone undecanoate in hypogonadal men. The Aging Male 2022; 25:134-144
Gynäkologische Endokrinologie
2. Nguyen, D.K., et al. The predictive value of anti-Mullerian hormone for natural conception leading to live birth in subfertile couples. Reprod Biomed Online. 2022; 44: 557-564.
3. Qiu, W., et al. Anti-Mullerian hormone has limited ability to predict fecundability in Chinese women: a preconception cohort study. https://doi.org/10.1016/j.rbmo.2022.02.014.
Reprod Biomed Online. 2022. 4. Falzarano, C., et al. Nonalcoholic Fatty Liver Disease in Women and Girls With Polycystic Ovary Syndrome. J Clin Endocrinol Metab. 2022; 107: 258-272.
5. Cho, I.Y., et al. Long or Irregular Menstrual Cycles and Risk of Prevalent and Incident Nonalcoholic Fatty Liver Disease. J Clin Endocrinol Metab. 2022; 107: e2309-e2317.
6. Berni, T.R., C.L. Morgan, and D.A. Rees Women With Polycystic Ovary Syndrome Have an Increased Risk of Major Cardiovascular Events: a Population Study. J Clin Endocrinol Metab. 2021; 106: e3369-e3380.
7. Duijkers, I.J.M., et al. Effect on ovarian activity and ovulation inhibition of different oral dosages of levonorgestrel. Contraception. 2022; 110: 6-15.
8. Thompson, R.L., et al. The use of serum segesterone acetate levels to assess adherence of trial participants with a contraceptive vaginal ring. Contraception. 2022; 108: 61-64.
9. Reed, S., et al. Unintended pregnancy in users of nomegestrol acetate and 17β-oestradiol (NOMAC-E2) compared with levonorgestrel-containing combined oral contraceptives: final results from the PRO-E2 study. Eur J Contracept Reprod Health Care. 2021; 26: 447-453.
10. Reed, S., et al. Prospective controlled cohort study on the safety of a monophasic oral contraceptive containing nomegestrol acetate (2.5mg) and 17β-oestradiol (1.5mg) (PRO-E2 study): risk of venous and arterial thromboembolism. Eur J Contracept Reprod Health Care. 2021; 26: 439-446.
11. Li, J., et al. Association of Risk for Venous Thromboembolism With Use of Low-Dose Extended- and Continuous-Cycle Combined Oral Contraceptives: A Safety Study Using the Sentinel Distributed Database. JAMA internal medicine. 2018; 178: 1482-1488.
12. Kaplan, S., et al. Long-term safety of extended levonorgestrel-containing oral contraceptives in the United States. Contraception. 2022; 105: 26-32.
13. Goldenberg, I., et al. Use of oral contraceptives in women with congenital long QT syndrome. Heart Rhythm. 2021. https://doi.org/10.1016/j.hrthm.2021.07.058.
14. Karlsson, T., et al. Time-Dependent Effects of Oral Contraceptive Use on Breast, Ovarian, and Endometrial Cancers. Cancer Res. 2021; 81: 1153-1162.
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Leitlinien in der Endokrinologie
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Deutsche Leitlinien (Auswahl, nur aufgeführt, wenn noch gültig)
Geschlechtsinkongruenz, Geschlechtsdysphorie und Trans-Gesundheit: S3-Leitlinie zur Diagnostik, Beratung und Behandlung (AWMF, n.d., https://doi.org/10.2018/Version)
S2k-Leitlinie Neuroendokrine Tumore (Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) et al., 2018, https://doi.org/10.1055/a-0604-2924)
Nicht alkoholische Fettlebererkrankungen (Roeb et al., 2015, https://doi.org/10.1055/s-0035-1553193)
S1-Leitlinie Gynäkomastie im Erwachsenenalter (Schanz et al., n.d., Retrieved from https://www.awmf.org/uploads/tx_szleitlinien/013-039l_S1_Gynaekomastie_Erwachsene_2016-05.pdf)
Operative Therapie benigner Schilddrüsenerkrankungen (Retrieved from https://www.awmf.org/uploads/tx_szleitlinien/088-007l_S2k_operative_Therapie_benigner_Schilddrüsenerkrankungen_2015-10.pdf)
S2k-Leitlinie Operative Therapie von Nebennierentumoren (Retrieved from https://www.awmf.org/uploads/tx_szleitlinien/088-008l_S2k_Operative-Therapie_Nebennierentumoren_2018-11.pdf)
Erhöhter TSH-Wert in der Hausarztpraxis (Retrieved from https://www.awmf.org/uploads/tx_szleitlinien/053-046l_S2k_erhoehter_TSH_Wert_2017-04.pdf)
S3-Leitlinie Antiresorptiva-assoziierte Kiefernekrosen (AR-ONJ) (Schiegnitz et al., n.d., Retrieved from https://www.awmf.org/uploads/tx_szleitlinien/007-091l_S3_Antiresorptiva-assoziierte-Kiefernekrosen-AR-ONJ_2018-12.pdf)
Europäische Leitlinien
2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol.(Grundy et al., 2018, https://doi.org/10.1161/CIR.0000000000000625)
Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome (Teede et al., 2018, https://doi.org/10.1093/humrep/dey256)
ESHRE Guideline: management of women with premature ovarian insufficiency.(European Society for Human Reproduction and Embryology (ESHRE) Guideline Group on POI et al., 2016, https://doi.org/10.1093/humrep/dew027)
Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors. (Fassnacht et al., 2016, https://doi.org/10.1530/EJE-16-0467)
European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults, in collaboration with the European Network for the Study of Adrenal Tumors(Fassnacht et al., 2018, https://doi.org/10.1530/EJE-18-0608)
European Society of Endocrinology Clinical Practice Guideline for long-term follow-up of patients operated on for a phaeochromocytoma or a paraganglioma (Plouin et al., 2016, https://doi.org/10.1530/EJE-16-0033)
Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency.(Husebye et al., 2014, https://doi.org/10.1111/joim.12162)
European Society of Endocrine Surgeons (ESES) and European Network for the Study of Adrenal Tumours (ENSAT) recommendations for the surgical management of adrenocortical carcinoma (Gaujoux & Mihai, 2017, https://doi.org/10.1002/bjs.10414)
European Society of Endocrinology Clinical Practice Guidelines for the management of aggressive pituitary tumours and carcinomas (Raverot et al., 2018, https://doi.org/10.1530/EJE-17-0796)
Clinical practice guidelines for the care of girls and women with Turner syndrome: proceedings from the 2016 Cincinnati International Turner Syndrome Meeting.(Gravholt et al., 2017, https://doi.org/10.1530/EJE-17-0430)
European Society of Endocrinology Clinical Guideline: Treatment of chronic hypoparathyroidism in adults.(Bollerslev et al., 2015, https://doi.org/10.1530/EJE-15-0628)
Clinical practice guideline on diagnosis and treatment of hyponatraemia (Spasovski et al., 2014, https://doi.org/10.1530/EJE-13-1020)
Leitlinien der European Thyroid Association ETA
2018 European Thyroid Association (ETA) Guidelines on the Diagnosis and Management of Central Hypothyroidism.(Persani et al., 2018, https://doi.org/10.1159/000491388)
2018 European Thyroid Association Guideline for the Management of Graves' Hyperthyroidism.(Kahaly et al., 2018, https://doi.org/10.1159/000490384)
2018 European Thyroid Association (ETA) Guidelines for the Management of Amiodarone-Associated Thyroid Dysfunction.(Bartalena et al., 2018, https://doi.org/10.1159/000486957)
European Thyroid Association Guidelines for Ultrasound Malignancy Risk Stratification of Thyroid Nodules in Adults: The EU-TIRADS.(Russ et al., 2017, https://doi.org/10.1159/000478927)
The 2015 European Thyroid Association Guidelines on Diagnosis and Treatment of Endogenous Subclinical Hyperthyroidism (Biondi et al., 2015, https://doi.org/10.1159/000438750)
The 2016 European Thyroid Association/European Group on Graves' Orbitopathy Guidelines for the Management of Graves' Orbitopathy.(Bartalena et al., 2016, https://doi.org/10.1159/000443828)
2013 European thyroid association guidelines for cervical ultrasound scan and ultrasound-guided techniques in the postoperative management of patients with thyroid cancer.(Leenhardt et al., 2013, https://doi.org/10.1159/000354537)
Leitlinien der American Thyroid Association ATA
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer (Haugen et al., 2015, https://doi.org/10.1089/thy.2015.0020)
2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum (Alexander et al., 2017, https://doi.org/10.1089/thy.2016.0457)
2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis (Ross et al., 2016, https://doi.org/10.1089/thy.2016.0229)
Revised American Thyroid Association Guidelines for the Management of Medullary Thyroid Carcinoma (Wells et al., 2015, https://doi.org/10.1089/thy.2014.0335)
Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement (Jonklaas et al., 2014, https://doi.org/10.1089/thy.2014.0028)
American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer (Smallridge et al., 2012, https://doi.org/10.1089/thy.2012.0302)
Praxisleitlinien der Endocrine Society:
Adrenal
Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency | 2018: https://www.endocrine.org/guidelines-and-clinical-practice/clinical-practice-guidelines/primary-aldosteronismThe Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment | 2016: https://www.endocrine.org/guidelines-and-clinical-practice/clinical-practice-guidelines/primary-aldosteronism
Diagnosis and Treatment of Primary Adrenal Insufficiency | 2016: https://www.endocrine.org/guidelines-and-clinical-practice/clinical-practice-guidelines/primary-adrenal-insufficiency
Treatment of Cushing’s Syndrome | 2015: https://www.endocrine.org/guidelines-and-clinical-practice/clinical-practice-guidelines/treatment-of-cushing-syndrome
Diagnosis and Treatment of Pheochromocytoma and Paraganglioma | 2014 https://doi.org/10.1210/jc.2014-1498
Diagnosis of Cushing's Syndrome | 2008 https://doi.org/10.1210/jc.2008-0125
Bone Health and Osteoporosis
Paget's Disease of Bone | 2014 https://doi.org/10.1210/jc.2014-2910Osteoporosis in Men | 2012 https://doi.org/10.1210/jc.2011-3045
Evaluation, Treatment, and Prevention of Vitamin D Deficiency | 2011 https://doi.org/10.1210/jc.2011-0385
Cardiovascular Endocrinology
The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment | 2016 https://www.endocrine.org/guidelines-and-clinical-practice/clinical-practice-guidelines/primary-aldosteronismEvaluation and Treatment of Hypertriglyceridemia | 2012 https://doi.org/10.1210/jc.2011-3213
Glucose Metabolism
Evaluation and Management of Adult Hypoglycemic Disorders | 2009 https://doi.org/10.1210/jc.2008-1410Endocrine Neoplasia and Cancer
Hypothalamic–Pituitary and Growth Disorders in Survivors of Childhood Cancer | 2018 https://www.endocrine.org/guidelines-and-clinical-practice/clinical-practice-guidelines/disorders-in-survivors-of-childhood-cancerFemale Reproductive Endocrinology
Evaluation and Treatment of Hirsutism in Premenopausal Women | 2018 https://www.endocrine.org/guidelines-and-clinical-practice/clinical-practice-guidelines/hirsutismFunctional Hypothalamic Amenorrhea | 2017 https://www.endocrine.org/guidelines-and-clinical-practice/clinical-practice-guidelines/hypothalamic-amenorrhea
Treatment of Symptoms of the Menopause | 2015 https://www.endocrine.org/guidelines-and-clinical-practice/clinical-practice-guidelines/treatment-of-menopause
Male Reproductive Endocrinology
Testosterone Therapy in Men with Hypogonadism ǀ 2018 https://www.endocrine.org/guidelines-and-clinical-practice/clinical-practice-guidelines/testosterone-therapyNeuroendocrinology
Hormonal Replacement in Hypopituitarism in Adults | 2016 https://www.endocrine.org/guidelines-and-clinical-practice/clinical-practice-guidelines/hormone-replacement-in-hypopituitarismAcromegaly | 2014 https://doi.org/10.1210/jc.2014-2700
Diagnosis and Treatment of Hyperprolactinemia | 2011 https://doi.org/10.1210/jc.2010-1692
Evaluation and Treatment of Adult Growth Hormone Deficiency | 2011 https://doi.org/10.1210/jc.2011-0179
Pituitary Incidentaloma | 2011 https://doi.org/10.1210/jc.2010-1048
Transgender Medicine
Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons | 2017 https://www.endocrine.org/guidelines-and-clinical-practice/clinical-practice-guidelines/gender-dysphoria-gender-incongruenceWie kann ich Mitglied werden?
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Telefonnummer 069 / 6301 5122 oder per E-Mail unter
andrea.willenberg@unimedizin-ffm.de zur Verfügung.
Andrea Willenberg
Sekretariat Prof. Dr. J. Bojunga
Stv. Direktor der Medizinischen Klinik 1
Schwerpunktleiter Endokrinologie
HS 11, 3. OG, R. 304
Universitätsklinikum / Goethe-Universität
Theodor-Stern-Kai 7
D 60590 Frankfurt